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Filtered Search Results
Biotium Carboxypeptidase A1 / CPA1 (Pancreatic Cancer Marker)(CPA1/2711), Biotin conjugate, 0.1mg/mL
Carboxypeptidase A1 (CPA1) is a secreted zinc metalloprotease that is highly expressed in pancreatic tissue. It catalyzes the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Human pancreatic procarboxypeptidase A exists as three different active forms, two of which are carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Cayman Chemical RAD51-IN-17 25mg
A RAD51 inhibitor; inhibits DNA damage-induced RAD51 foci formation in MDA-MB-231 TNBC cells at 10 µM; enhances irradiation-induced reductions in the proliferation of MDA-MB-231 cells at 10 µM
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Sino Biological Recombinant Human CD70/CD27 Ligand Protein (Site-Specific PE Conjugation, ECD, Trimer, His Tag)
A DNA sequence encoding the human CD70 (NP_001243.1) (Gln 39-Pro 193) was expressed with a N-terminal polyhistidine tag. This construct has a trimer design.The protein is site-specifically conjugated with PE (Excitation = 495-566 nm, Emission Max.= 575 nm).
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ABclonal Technology MATN2 Rabbit pAb
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This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
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Meso Scale Discovery R-PLEX Rat HAVCR1/KIM-1 ASYQP
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The R-PLEX Rat HAVCR1 (KIM-1) Assay from Meso Scale Diagnostics is a 96-well electrochemiluminescent immunoassay for measuring Kidney Injury Molecule-1 (KIM-1) in rat serum plasma urine and tissue culture supernatants It uses MSD s SULFO-TAG labels and multi-array technology for sensitive rapid KIM-1 quantification a key biomarker of kidney injury The kit includes a 96-well plate with anti-KIM-1 capture antibody detection antibody read buffer sample diluent calibrators and controls
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Beckman Coulter CD58 PUR 5 MGS CLONE ALCD
CD58 PUR 5 MGS CLONE ALCD
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Biotium Perforin-1 (Pore Forming Protein) (Apoptosis Marker) (PRF1/2468), CF740 conjugate, 0.1mg/mL
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. The expression of perforin is reportedly upregulated in activated CD8 T-cells, natural killer cells and some CD4 T-cells.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of
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Biotium Annexin A1 / (Hairy Cell Leukemia Marker)(ANXA1/3566), CF647 conjugate, 0.1mg/mL
Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL). Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue
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Sino Biological Human respiratory syncytial virus (RSV) Fusion Glycoprotein / RSV-F ELISA Pair Set 5Plates
Human respiratory syncytial virus (RSV) Fusion Glycoprotein / RSV-F ELISA Pair Set
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ABclonal Technology OXSR1 Rabbit pAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.
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Biotium CD79b (B-Cell Marker)(rIGB/1842), CF740 conjugate, 0.1mg/mL
CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Biotium Annexin A1 / (Hairy Cell Leukemia Marker)(ANXA1/3566), CF740 conjugate, 0.1mg/mL
Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL). Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue
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Human IFNG ELISA Pair Set 15PP (Sino Biological)
Each vial contains 19 ng of recombinant Human Interferon Gamma/IFN gamma/IFNG. Reconstitute with 1 mL Dilution Buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial in Dilution Buffer, and a high standard of 1400 pg/mL is recommended.
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ABclonal Technology SGOL1 Rabbit pAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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The protein encoded by this gene is a member of the shugoshin family, believed to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression leads to premature loss of centromeric cohesion, sister chromatid mis-segregation, and mitotic arrest. This protein also protects a subset of cohesin on chromosome arms during prophase. An isoform lacking exon 6 plays a role in centriolar cohesion. Mutations in this gene are linked to Chronic Atrial and Intestinal Dysrhythmia (CAID) syndrome, which involves Sick Sinus Syndrome and Chronic Intestinal Pseudo-obstruction. Fibroblasts from CAID patients show increased cell proliferation and higher senescence rates. Pseudogenes of this gene are found on chromosomes 1 and 7, and alternative splicing generates multiple transcript variants.
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Sino Biological Recombinant Human DcR3/TNFRSF6B Protein (His Tag), Biotinylated
A DNA sequence encoding the Human TNFRSF6B (O95407) (Met1-Ser195) was expressed with a polyhistidine tag at the C-terminus. The purified protein was biotinylated in vitro.
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